Ammonia → HCID 86744027, compound

HRID 2107188Notes

Reaction equation

HRID 2107188 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10][C:11](=[O:25])[NH:12][C:13]2[S:14][CH:15]=[C:16]([C:18](=O)[C:19]([O:21][CH2:22][CH3:23])=[O:20])[N:17]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[S:26]1[CH2:32][C:30](=[O:31])[N:29]([CH2:33][C:34]([OH:36])=[O:35])[C:27]1=[S:28].[Cl-].[NH4+].N>C(O)C>[CH3:27][N:29]([CH3:33])[CH:30]=[O:31].[CH3:27][N:29]([CH3:33])[CH:30]=[O:31].[CH2:22]([O:21][C:19]([C:18](=[C:32]1[S:26][C:27](=[S:28])[N:29]([CH2:33][C:34]([OH:36])=[O:35])[C:30]1=[O:31])[C:16]1[N:17]=[C:13]([NH:12][C:11]([NH:10][C:7]2[CH:8]=[CH:9][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)=[O:25])[S:14][CH:15]=1)=[O:20])[CH3:23]

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053506Ethyl 2-(3-p-nitrophenylureido)thiazol-4-ylglyoxylate

Product 1

HCID 86744027HCID 86744027, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a procedure similar to that described in Example 1, the desired compound was prepared from 3.7 g of ethyl 2-(3-p-nitrophenylureido)thiazol-4-ylglyoxylate, 1.9 g of rhodanine-3-acetic acid, 1 g of ammonium chloride, 1 ml of 28% v/v aqueous ammonia and 40 ml of ethanol. The resulting product was a yellow powder having the following physical properties.

Sources & evidence

ORD record
ord-a9b979cd8bea4aad8bedf003a6918c1f
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

Loading…