Ammonia → HCID 54056607, compound

HRID 2107189Notes

Reaction equation

HRID 2107189 reaction equation
[CH3:1][NH:2][C:3](=[O:17])[NH:4][C:5]1[S:6][CH:7]=[C:8]([C:10](=O)[C:11]([O:13][CH2:14][CH3:15])=[O:12])[N:9]=1.[S:18]1[CH2:24][C:22](=[O:23])[N:21]([CH2:25][C:26]([OH:28])=[O:27])[C:19]1=[S:20].[Cl-].[NH4+].N>C(O)C>[CH2:14]([O:13][C:11]([C:10](=[C:24]1[S:18][C:19](=[S:20])[N:21]([CH2:25][C:26]([OH:28])=[O:27])[C:22]1=[O:23])[C:8]1[N:9]=[C:5]([NH:4][C:3]([NH:2][CH3:1])=[O:17])[S:6][CH:7]=1)=[O:12])[CH3:15]

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053518HCID 15053518, compound

Product 1

HCID 54056607HCID 54056607, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a procedure similar to that described in Example 1, the desired compound was prepared from 3.17 g of ethyl 2-(3-methylureido)thiazol-4-ylglyoxylate, 2.2 g of rhodanine-3-acetic acid, 1.2 g of ammonium chloride, 1.2 ml of 28% v/v aqueous ammonia and 50 ml of ethanol. The resulting product was a yellow powder having the following physical properties.

Sources & evidence

ORD record
ord-bb946521c76f43168ab7a3220b7b87fa
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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