Ammonia → HCID 53858537, compound

HRID 2107191Notes

Reaction equation

HRID 2107191 reaction equation
[CH:1]1([NH:7][C:8](=[O:22])[NH:9][C:10]2[S:11][CH:12]=[C:13]([C:15](=O)[C:16]([O:18][CH2:19][CH3:20])=[O:17])[N:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[S:23]1[CH2:29][C:27](=[O:28])[N:26]([CH2:30][C:31]([OH:33])=[O:32])[C:24]1=[S:25].[Cl-].[NH4+].N>C(O)C>[CH:1]1([NH:7][C:8](=[O:22])[NH:9][C:10]2[S:11][CH:12]=[C:13]([C:15](=[C:29]3[S:23][C:24](=[S:25])[N:26]([CH2:30][C:31]([OH:33])=[O:32])[C:27]3=[O:28])[C:16]([O:18][CH2:19][CH3:20])=[O:17])[N:14]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053520HCID 15053520, compound

Product 1

HCID 53858537HCID 53858537, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a procedure similar to that described in Example 1, the desired compound was prepared using 1 g of ethyl 2-(3-cyclohexylureido)thiazol-4-ylglyoxylate, 0.58 g of rhodanine-3-acetic acid, 0.3 g of ammonium chloride, 0.3 ml of 28% v/v aqueous ammonia and 10 ml of ethanol. The resulting product was a yellow powder having the following physical properties.

Sources & evidence

ORD record
ord-6def78f11c0b4d1f976874a3e5ea6c22
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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