Ammonium Chloride → Ammonia

HRID 2107194Notes

Reaction equation

HRID 2107194 reaction equation
[CH2:1]([N:3]([CH2:11][CH3:12])[C:4]1[S:5][CH:6]=[C:7]([CH:9]=O)[N:8]=1)[CH3:2].[S:13]1[CH2:19][C:17](=[O:18])[N:16]([CH2:20][C:21]([OH:23])=[O:22])[C:14]1=[S:15].[Cl-].[NH4+]>C(O)C>[NH3:3].[CH2:1]([N:3]([CH2:11][CH3:12])[C:4]1[S:5][CH:6]=[C:7]([CH:9]=[C:19]2[S:13][C:14](=[S:15])[N:16]([CH2:20][C:21]([OH:23])=[O:22])[C:17]2=[O:18])[N:8]=1)[CH3:2]

Participants

6

Reactant 3

HCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053529HCID 15053529, compound

Product 2

HCID 222AmmoniaHCID 54338680HCID 54338680, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The reaction described in Example 1 was repeated, but using 1.2 g of 2-diethylaminothiazole-4-carbaldehyde, 1 g of rhodanine-3-acetic acid. 0.8 g of ammonium chloride. 0.8 ml of 28% v/v aqueous ammonia, and 25 ml of ethanol, giving the title compound as yellowish-brown needles.

Sources & evidence

ORD record
ord-416656ab54f046ff818e74dcefb32a96
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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