Ammonia → HCID 54253496, compound

HRID 2107197Notes

Reaction equation

HRID 2107197 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][C:9](=[S:23])[NH:10][C:11]1[S:12][CH:13]=[C:14]([C:16](=O)[C:17]([O:19][CH2:20][CH3:21])=[O:18])[N:15]=1.[S:24]1[CH2:30][C:28](=[O:29])[N:27]([CH2:31][C:32]([OH:34])=[O:33])[C:25]1=[S:26].[Cl-].[NH4+].N>C(O)C>[CH2:20]([O:19][C:17]([C:16](=[C:30]1[S:24][C:25](=[S:26])[N:27]([CH2:31][C:32]([OH:34])=[O:33])[C:28]1=[O:29])[C:14]1[N:15]=[C:11]([NH:10][C:9]([NH:8][C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[F:1])=[S:23])[S:12][CH:13]=1)=[O:18])[CH3:21]

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053509HCID 15053509, compound

Product 1

HCID 54253496HCID 54253496, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a procedure similar to that described in Example 1, the desired compound was prepared from 7 g of ethyl 2-(3-o-fluorophenylthioureido)thiazol-4-ylglyoxylate, 3.8g of rhodanine-3-acetic acid, 2 g of ammonium chloride, ml of 28% v/v aqueous ammonia and 100 ml of ethanol. The resulting product was a yellow powder having the following physical properties.

Sources & evidence

ORD record
ord-3a827dc87fd9447692cba8dec550de70
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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