Ammonia → HCID 53680015, compound

HRID 2107202Notes

Reaction equation

HRID 2107202 reaction equation
[C:1]1([CH3:15])[C:2]([NH:7][C:8]2[S:9][CH:10]=[C:11]([CH:13]=O)[N:12]=2)=[CH:3][CH:4]=[CH:5][CH:6]=1.[S:16]1[CH2:22][C:20](=[O:21])[N:19]([CH2:23][C:24]([OH:26])=[O:25])[C:17]1=[S:18].[Cl-].[NH4+].N>C(O)C>[C:1]1([CH3:15])[C:2]([NH:7][C:8]2[S:9][CH:10]=[C:11]([CH:13]=[C:22]3[S:16][C:17](=[S:18])[N:19]([CH2:23][C:24]([OH:26])=[O:25])[C:20]3=[O:21])[N:12]=2)=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 23047606HCID 23047606, compound

Product 1

HCID 53680015HCID 53680015, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following a procedure similar to that described in Example 1, the desired compound was prepared from 1.12 g of 2-(o-toluidino)thiazole-4-carbaldehyde, 0.87 g of rhodanine-3-acetic acid, 0.5 g of ammonium chloride, 0.5 ml of 28% v/v aqueous ammonia and 15 ml of ethanol. The resulting product was an orange powder having the following physical properties.

Sources & evidence

ORD record
ord-df82c0edf7be4ef0baf8cc8bc6f5b640
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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