Phthaloyl chloride → HCID 131716435, compound

Participants

Reaction Conditions

Reaction Steps

0.7 g of phthaloyl dichloride was added dropwise under ice-cooling to a solution of 1.19 g of 5-[1-(2-aminothiazol-4-yl)-1-ethoxycarbonylmethylene]rhodanine-3-acetic acid in 8 ml of tetrahydrofuran. The resulting mixture was stirred for 6 hours under ice-cooling and then heated at 60° C. for 4 hours. The crystals which precipitated out after cooling were collected by filtration and recrystallized from ethanol. The resulting product was a yellow powder having the following physical properties.

Provenance & Evidence