HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-[2-(p-Fluoroanilino)thiazol-4-ylmethylene]rhodanine-3-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 3-Thiazolidineacetic acid, 4-oxo-2-thioxo- | HCID 79793 | — |
| Reactant | 2-(p-Fluoroanilino)thiazole-4-carbaldehyde | HCID 15053572 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-[2-(p-Fluoroanilino)thiazol-4-ylmethylene]rhodanine-3-acetic acid | HCID 53769738 | — |
Reaction Steps
The reaction described in Example 1 was repeated, but using 1 g of 2-(p-fluoroanilino)thiazole-4-carbaldehyde, 0.85 g of rhodanine-3-acetic acid, 0.5 g of ammonium chloride, 0.5 ml of 28% v/v aqueous ammonia, and 10 ml of ethanol, giving the title compound as an orange powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04933355 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-181248d3b6ca4042be7e10e620504046 |
| Source note | uspto-grants-1990_06 |