Ammonia → HCID 54005559, compound

HRID 2107210Notes

Reaction equation

HRID 2107210 reaction equation
[F:1][C:2]([F:18])([F:17])[C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:16]=1)[NH:6][C:7]1[S:8][CH:9]=[C:10]([CH:12]=O)[N:11]=1.[S:19]1[CH2:25][C:23](=[O:24])[N:22]([CH2:26][C:27]([OH:29])=[O:28])[C:20]1=[S:21].[Cl-].[NH4+].N>C(O)C>[F:1][C:2]([F:18])([F:17])[C:3]1[CH:4]=[C:5]([CH:14]=[CH:15][CH:16]=1)[NH:6][C:7]1[S:8][CH:9]=[C:10]([CH:12]=[C:25]2[S:19][C:20](=[S:21])[N:22]([CH2:26][C:27]([OH:29])=[O:28])[C:23]2=[O:24])[N:11]=1

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053574HCID 15053574, compound

Product 1

HCID 54005559HCID 54005559, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The reaction described in Example 1 was repeated, but using 1 g of 2-(m-trifluoromethylanilino)thiazole-4-carbaldehyde, 0.7 g of rhodanine-3-acetic acid, 0.5 g of ammonium chloride, 0.5 ml of 28% v/v aqueous ammonia, and 10 ml of ethanol, giving the title compound as yellowish-orange prisms.

Sources & evidence

ORD record
ord-ca8a7a8c565247d8b3084192c255f7e8
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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