HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 5-(2-Ethylaminothiazol-4-ylmethylene)rhodanine-3-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | 3-Thiazolidineacetic acid, 4-oxo-2-thioxo- | HCID 79793 | — |
| Reactant | 2-Ethylaminothiazole-4-carbaldehyde | HCID 15053575 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-(2-Ethylaminothiazol-4-ylmethylene)rhodanine-3-acetic acid | HCID 54503251 | 84.8% |
Reaction Steps
The reaction described in Example 1 was repeated, but using 1.27 g of 2-ethylaminothiazole-4-carbaldehyde, 1.3 g of rhodanine-3-acetic acid, 1 g of ammonium chloride, 1 ml of 28% v/v aqueous ammonia and 30 ml of ethanol, giving 1.9 g of the title compound as yellow needles.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04933355 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-705d432c13bb4592be46cb1ba9cbfb2a |
| Source note | uspto-grants-1990_06 |