Ammonia → HCID 54346284, compound

HRID 2107216Notes

Reaction equation

HRID 2107216 reaction equation
[N:1]1([C:7]2[S:8][CH:9]=[C:10]([CH:12]=O)[N:11]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[S:14]1[CH2:20][C:18](=[O:19])[N:17]([CH2:21][C:22]([OH:24])=[O:23])[C:15]1=[S:16].[Cl-].[NH4+].N>C(O)C>[N:1]1([C:7]2[S:8][CH:9]=[C:10]([CH:12]=[C:20]3[S:14][C:15](=[S:16])[N:17]([CH2:21][C:22]([OH:24])=[O:23])[C:18]3=[O:19])[N:11]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053580HCID 15053580, compound

Product 1

HCID 54346284HCID 54346284, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The reaction described in Example 1 was repeated. but using 1.8 g of 2-piperidinothiazole-4-carbaldehyde, 1.4 g of rhodanine-3-acetic acid, 1.0 g of ammonium chloride, 1 ml of 28% v/v aqueous ammonia and 40 ml of ethanol, giving the title compound as yellow needles.

Sources & evidence

ORD record
ord-65aeefe6243a44b1b8b749419935b6d1
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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