Ammonia → HCID 53704186, compound

HRID 2107220Notes

Reaction equation

HRID 2107220 reaction equation
[CH:1]([NH:4][C:5]1[S:6][CH:7]=[C:8]([CH:10]=O)[N:9]=1)([CH3:3])[CH3:2].[S:12]1[CH2:18][C:16](=[O:17])[N:15]([CH2:19][C:20]([OH:22])=[O:21])[C:13]1=[S:14].[Cl-].[NH4+].N>C(O)C>[CH:1]([NH:4][C:5]1[S:6][CH:7]=[C:8]([CH:10]=[C:18]2[S:12][C:13](=[S:14])[N:15]([CH2:19][C:20]([OH:22])=[O:21])[C:16]2=[O:17])[N:9]=1)([CH3:2])[CH3:3]

Participants

6

Reactant 4

HCID 222AmmoniaHCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053584HCID 15053584, compound

Product 1

HCID 53704186HCID 53704186, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The reaction described in Example 1 was repeated, but using 2.7 g of 2-isopropylaminothiazole-4-carbaldehyde, 2.3 g of rhodanine-3-acetic acid, 1.7 g of ammonium chloride, 1.7 ml of 28% v/v aqueous ammonia and 50 ml of ethanol, giving the title compound as dark red needles.

Sources & evidence

ORD record
ord-43122e8c08db4684b417308c0cb49db2
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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