Ammonium Chloride → Ammonia

HRID 2107221Notes

Reaction equation

HRID 2107221 reaction equation
[CH2:1]([NH:8][C:9]1[S:10][CH:11]=[C:12]([CH:14]=O)[N:13]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[S:16]1[CH2:22][C:20](=[O:21])[N:19]([CH2:23][C:24]([OH:26])=[O:25])[C:17]1=[S:18].[Cl-].[NH4+]>C(O)C>[NH3:8].[CH2:1]([NH:8][C:9]1[S:10][CH:11]=[C:12]([CH:14]=[C:22]2[S:16][C:17](=[S:18])[N:19]([CH2:23][C:24]([OH:26])=[O:25])[C:20]2=[O:21])[N:13]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

6

Reactant 3

HCID 25517Ammonium ChlorideHCID 797933-Thiazolidineacetic acid, 4-oxo-2-thioxo-HCID 15053585HCID 15053585, compound

Product 2

HCID 222AmmoniaHCID 54188864HCID 54188864, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The reaction described in Example 1 was repeated, but using 0.58 g of 2-benzylaminothiazol-4-carbaldehyde, 0.5 g of rhodanine-3-acetic acid 0.3 g of ammonium chloride. 0.3 ml of 28% v/v aqueous ammonia and 40 ml of ethanol, giving the title compound as yellow needles.

Sources & evidence

ORD record
ord-e595a23822c5484f9dc5a8bd1932c075
Source dataset
uspto-grants-1990_06
Patent number
US04933355

Reaction notes

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