HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-(diethylamino)-1,3-thiazole-4-carboxylate → 2-(N,N-Diethylamino)-4-(hydroxymethyl)thiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-(diethylamino)-1,3-thiazole-4-carboxylate | HCID 12966399 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-(N,N-Diethylamino)-4-(hydroxymethyl)thiazole | HCID 18758970 | — |
Reaction Steps
The reaction described in Preparation 15 was then repeated, but using 1.9 g of the above ester, 0.31 g of lithium aluminum hydride, and 40 ml of tetrahydrofuran, giving 2-diethylaminothiazol-4-ylmethanol as colorless prisms.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04933355 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-5fd4932351eb410abfc3e006ec8e17eb |
| Source note | uspto-grants-1990_06 |