Pyrrolidone carboxylic acid → HCID 20061777, compound

HRID 2107319Notes

Reaction equation

HRID 2107319 reaction equation
[NH:1]1[C:5](=[O:6])[CH2:4][CH2:3][C@H:2]1[C:7]([OH:9])=O.O=C1[NH:15][CH:14](C(O)=O)[CH2:13]C1.C(CN)O>>[NH:1]1[CH:2]([C:7]2[O:9][CH2:13][CH2:14][N:15]=2)[CH2:3][CH2:4][C:5]1=[O:6]

Participants

4

Reactant 3

HCID 499Pyrrolidone carboxylic acidHCID 700EthanolamineHCID 7405L-Pyroglutamic Acid

Product 1

HCID 20061777HCID 20061777, compound

Procedure

In a similar manner, pyroglutamic acid, i.e. 5-oxo-2-pyrrolidinecarboxylic acid, where R=H and m=0 in the above formula (I), can be condensed with ethanolamine and cyclodehydrated to form the corresponding monomer 2-(2-pyrrolidon-5-yl)-2-oxazoline.

Sources & evidence

ORD record
ord-d2829113b11a43aa8346fc5feb14b597
Source dataset
uspto-grants-1990_06
Patent number
US04933463

Reaction notes

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