HCID 14839448, compound → Imidazo(4,5-b)pyridine

HRID 2107339Notes

Reaction equation

HRID 2107339 reaction equation
S[C:2]1[NH:3][C:4]2[C:5]([N:10]=1)=[N:6][CH:7]=[CH:8][CH:9]=2.Cl.C1(NC2C=CC=CC=2CCl)CCCC1>C(O)C>[NH:3]1[C:4]2[C:5](=[N:6][CH:7]=[CH:8][CH:9]=2)[N:10]=[CH:2]1

Participants

4

Reactant 2

HCID 14839448HCID 14839448, compoundHCID 178527819HCID 178527819, compound

Product 1

HCID 67504Imidazo(4,5-b)pyridine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Mercaptoimidazo[4,5-b]pyridine and 2-(N-cylopentylamino)benzyl chloride hydrochloride were reacted in an aqueous ethanol solution to obtain 2-[2-(N-cyclopentylamino)benzylthio[-imidazo[4,5-b]pyridine in the same manner as in Example 9-(2). The obtained 2-[2-(N-cyclopentylamino)benzylthio]imidazo[4,5-b]pyridine was oxidized by m-chloroperbenzoic acid in chloroform in the same manner in Example 9-(3) to give 2-[2-(N-cyclopentylamino)benzylsulfinyl]imidazo[4,5-b]pyridine as a pale yellow crystalline product. m.p.: 134° C. (decompn.)

Sources & evidence

ORD record
ord-71a1d152df244e14af615d7a91daf7e1
Source dataset
uspto-grants-1990_06
Patent number
US04933458

Reaction notes

Loading…