反应详情

温度

100 °C

A mixture of 3.0 g of 6-chloro-3-(1-methyl-4-piperidinyl)-1H-indazole and 8 ml of benzoyl chloride was heated at 100° C. on a steam bath for 4 hrs. The reaction mixture was cooled to ambient temperature and ether was added. The precipitate was filtered, washed with ether and dried. Recrystallization from ethanol (twice) yielded 2.6 g (56%) of product, mp 248°-250° C.

1. temperatureThe reaction mixture was cooled to ambient temperature
2. filtrationThe precipitate was filtered
3. washwashed with ether
4. customdried
5. customRecrystallization from ethanol (twice)