2,2-Difluoro-2-pyridin-2-ylethaneamine → N-(2,2-Difluoro-2-pyridin-2-yl-ethyl)-2-[3-(2,2-difluoro-2-pyridin-4-yl-ethylamino)-6-methyl-2-oxo-2H-pyrazin-1-yl]-acetamide
Reaction equation
[F:1][C:2]([CH2:3][NH:4][c:5]1[c:6](=[O:16])[n:7]([CH2:12][C:13](=[O:14])[OH:15])[c:8]([CH3:11])[cH:9][n:10]1)([c:17]1[cH:18][cH:19][n:20][cH:21][cH:22]1)[F:23].[F:24][C:25]([CH2:26][NH2:27])([c:28]1[n:29][cH:30][cH:31][cH:32][cH:33]1)[F:34]>>[F:1][C:2]([CH2:3][NH:4][c:5]1[c:6](=[O:16])[n:7]([CH2:12][C:13](=[O:15])[NH:27][CH2:26][C:25]([F:24])([c:28]2[n:29][cH:30][cH:31][cH:32][cH:33]2)[F:34])[c:8]([CH3:11])[cH:9][n:10]1)([c:17]1[cH:18][cH:19][n:20][cH:21][cH:22]1)[F:23]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-75759f9062d04ad0af43f4d1363ef2f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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