HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitrobenzyl bromide → 4-Nitrobenzyl (2S,4R)-4-hydroxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitrobenzyl bromide | HCID 66011 | — |
| Reactant | trans-4-Hydroxy-1-(4-nitrobenzyloxycarbonyl)-L-proline | HCID 10566895 | — |
| Product | 4-Nitrobenzyl (2S,4R)-4-hydroxy-1-(4-nitrobenzyloxycarbonyl)pyrrolidine-2-carboxylate | HCID 13644619 | — |
Reaction Steps
In the same manner as described in Reference Example 1-2 but using 500 mg of trans-1-p-nitrobenzyloxycarbonyl-4-hydroxy-L-proline and 383 mg of p-nitrobenzyl bromide, trans-1-p-nitrobenzyloxycarbonyl-4-hydroxy-L-proline p-nitrobenzyl ester was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04933333 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-45eab63819fa4e8e9de4b0b9242738ca |
| Source note | uspto-grants-1990_06 |