Water → HCID 131716437, compound

HRID 2107557Notes

Reaction equation

HRID 2107557 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[N:7]1[CH2:12][CH2:11][N:10]([CH2:13][CH2:14][CH2:15][C:16]2[N:17]=[C:18]([NH2:21])[S:19][CH:20]=2)[CH2:9][CH2:8]1.[OH2:22]>>[OH2:22].[CH3:20][C:16]1[N:17]=[C:18]([NH2:21])[S:19][C:15]=1[CH2:14][CH2:13][N:10]1[CH2:11][CH2:12][N:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[CH2:8][CH2:9]1.[CH3:20][C:16]1[N:17]=[C:18]([NH2:21])[S:19][C:15]=1[CH2:14][CH2:13][N:10]1[CH2:11][CH2:12][N:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[CH2:8][CH2:9]1

Participants

3

Reactant 2

HCID 962WaterHCID 14839510HCID 14839510, compound

Product 1

HCID 131716437HCID 131716437, compound

Procedure

mp 135°-150° C. and EXAMPLE 1i 4-[3-[4-(2-Pyridinyl)-1-piperazinyl]-propyl]-2-thiazolamine, containing 1/4 of a mole of water; mp 132°-137° C.

Sources & evidence

ORD record
ord-2a38916e006849d497efca4883831d7f
Source dataset
uspto-grants-1990_06
Patent number
US04935424

Reaction notes

Loading…