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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2107563Generated: October 30, 2026

Ethyl Acetate → Acetamide, N-(2-amino-2-methylpropyl)-

https://huagongshe.com/reaction/2107563

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
Reactant2-MethylpropylenediamineHCID 13128—
ProductAcetamide, N-(2-amino-2-methylpropyl)-HCID 979377457.4%

Reaction Conditions

Temperature100 °C

Reaction Steps

A mixture of 26.4 g (0.3 mol) of ethyl acetate and 79.2 g (0.9 mol) of 1,2-diamino-2-methylpropane was heated at 100° C. in a pressure bomb for 36 hours. The reaction mixture was evaporated in vacuo and distilled to give 22.4 g (57.4%) of product; boiling point 100° C./0.1 mmHg. This product was identified by NMR and IR spectroscopy.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04935421
Source datasetuspto-grants-1990_06
ORD IDord-5599c921531c4e34abdaadcb2700b428
Source noteuspto-grants-1990_06