Benzene → HCID 14049336, compound

HRID 2107692Notes

Reaction equation

HRID 2107692 reaction equation
[CH2:1]([Sn:11](Cl)([CH2:22][C:23]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)([CH3:25])[CH3:24])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[C:18]([F:21])([F:20])[F:19])[C:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)([CH3:4])[CH3:3].[S-:33][C:34]#[N:35].[K+].C1C=CC=CC=1>O>[CH2:1]([Sn:11]([N:35]=[C:34]=[S:33])([CH2:22][C:23]([C:26]1[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=1)([CH3:25])[CH3:24])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[C:18]([F:21])([F:20])[F:19])[C:2]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)([CH3:4])[CH3:3]

Participants

5

Reactant 3

HCID 241BenzeneHCID 516872Potassium thiocyanateHCID 14049250HCID 14049250, compound

Product 1

HCID 14049336HCID 14049336, compoundYield 96.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Dineophyl-orthotrifluoromethylphenyltin chloride (6 g, 10.6 mmol) prepared in Example 5, potassium thiocyanate (1.5 g, 15.9 mmol), benzene (40 g) and water (10 g) were charged into a flask and the mixture was refluxed for 2 hours. The aqueous layer was removed and the organic layer was washed with water and filtered. Evaporation of the benzene under reduced pressure gave 6.0 g of dineophyl-orthotrifluoromethylphenyltin isothiocyanate as a colorless viscous liquid.

Workup

  1. temperaturethe mixture was refluxed for 2 hours
  2. customThe aqueous layer was removed
  3. washthe organic layer was washed with water
  4. filtrationfiltered
  5. customEvaporation of the benzene under reduced pressure

Sources & evidence

ORD record
ord-15073a2a05d7422e903ae88d3ae1cfa0
Source dataset
uspto-grants-1990_06
Patent number
US04935408

Reaction notes

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