HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 13393787, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 4H-1-Benzopyran-4-one, 7-fluoro-2,3-dihydro-2-phenyl- | HCID 5270543 | — |
| Product | HCID 13393787 | HCID 13393787 | — |
Reaction Steps
As in example 1, but using 10 g 7-fluoro-flavanone, 100 ml dimethylformamide and 15 ml phosphorous oxychloride. Reaction time is one hour and a half at 50° C. After hydrolysis and usual work up, the residual solid is recrystallised in hexane. Pure yellow crystalline 4-chloro-7-fluoro-3-formyl-flav-3-ene is obtained; m.p. 110°-112° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04935441 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-e6f6a12e08b045b6a3e95f2a065d5615 |
| Source note | uspto-grants-1990_06 |