HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 13393792, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Phosphorus oxychloride | HCID 24813 | — |
| Reactant | 5,6,7-Trimethoxy-2-phenyl-2,3-dihydro-4H-1-benzopyran-4-one | HCID 12405137 | — |
| Product | HCID 13393792 | HCID 13393792 | — |
Reaction Steps
As in example 1, but using 15 g 5,6,7-trimethoxyflavanone, 150 ml dimethylformamide and 26 ml phosphorous oxychloride. Reaction time is forty eight hours at room temperature. After hydrolysis and usual work up, the residual solid is purified by preparative HPLC and the best fractions are crystallised in hexane. 4-chloro-3-formyl-5,6,7-trimethoxyflav-3-ene is obtained as yellow crystals; m.p. 84°-87° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04935441 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-3f2c4f1dea9a4de7846c1472f60509c2 |
| Source note | uspto-grants-1990_06 |