Aluminium lithium hydride → HCID 23046459, compound

HRID 2107735Notes

Reaction equation

[CH3:1][S:2]([C:5]1[NH:6][CH:7]=[C:8]([C:10](=O)[CH2:11][C:12]2[CH:17]=[C:16]([C:18]([CH3:21])([CH3:20])[CH3:19])[C:15]([OH:22])=[C:14]([C:23]([CH3:26])([CH3:25])[CH3:24])[CH:13]=2)[CH:9]=1)(=[O:4])=[O:3].[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[CH3:1][S:2]([C:5]1[NH:6][CH:7]=[C:8]([CH2:10][CH2:11][C:12]2[CH:17]=[C:16]([C:18]([CH3:19])([CH3:20])[CH3:21])[C:15]([OH:22])=[C:14]([C:23]([CH3:26])([CH3:25])[CH3:24])[CH:13]=2)[CH:9]=1)(=[O:4])=[O:3]

Participants

Reactant 2

HCID 21226445Aluminium lithium hydride

HCID 23046390HCID 23046390, compound

Product 1

HCID 23046459HCID 23046459, compound

Procedure

For example, using 2-methylsulfonyl-4-[2-(3,5-di-t-butyl-4-hydroxyphenyl)-1-oxo-ethyl]pyrrole in this generation reaction together with eight molar equivalents of LAH yields 2-methylsulfonyl-4-[2-(3,5-di-t-butyl-4-hydroxyphenyl)ethyl]pyrrole (a compound according to Formula X wherein: m is 2; n is 0; R is H; and X is SO2CH3 ; and Y and Z are each H). Likewise, using 3-(3,5-di-t-butyl-4-hydroxybenzoyl)pyrrole in this general reaction together with eight molar equivalents of LAH yields 3-(3,5-di-t-butyl-4-hydroxybenzyl)pyrrole (a compound according to Formula X wherein: m is 1; n is 0; R is H; and X, Y and Z are each H).

Sources & evidence

ORD record: ord-75240ecf3b1d4463a8e0e7e953e6518c
Source dataset: uspto-grants-1990_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04935440

Reaction notes

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