3-(3,5-Di-t-butyl-4-hydroxybenzoyl)pyrrole → HCID 14852436, compound

HRID 2107736Notes

Reaction equation

HRID 2107736 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([CH:15]=[C:16]([C:19]([CH3:22])([CH3:21])[CH3:20])[C:17]=1[OH:18])[C:8]([C:10]1[CH:14]=[CH:13][NH:12][CH:11]=1)=O)([CH3:4])([CH3:3])[CH3:2].[H-].[H-].[H-].[H-].[Li+].[Al+3]>>[C:1]([C:5]1[CH:6]=[C:7]([CH:15]=[C:16]([C:19]([CH3:22])([CH3:21])[CH3:20])[C:17]=1[OH:18])[CH2:8][C:10]1[CH:14]=[CH:13][NH:12][CH:11]=1)([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 148524113-(3,5-Di-t-butyl-4-hydroxybenzoyl)pyrroleHCID 21226445Aluminium lithium hydride

Product 1

HCID 14852436HCID 14852436, compound

Procedure

For example, using 2-methylsulfonyl-4-[2-(3,5-di-t-butyl-4-hydroxyphenyl)-1-oxo-ethyl]pyrrole in this generation reaction together with eight molar equivalents of LAH yields 2-methylsulfonyl-4-[2-(3,5-di-t-butyl-4-hydroxyphenyl)ethyl]pyrrole (a compound according to Formula X wherein: m is 2; n is 0; R is H; and X is SO2CH3 ; and Y and Z are each H). Likewise, using 3-(3,5-di-t-butyl-4-hydroxybenzoyl)pyrrole in this general reaction together with eight molar equivalents of LAH yields 3-(3,5-di-t-butyl-4-hydroxybenzyl)pyrrole (a compound according to Formula X wherein: m is 1; n is 0; R is H; and X, Y and Z are each H).

Sources & evidence

ORD record
ord-7aec58b2db684a57865046edbb023f47
Source dataset
uspto-grants-1990_06
Patent number
US04935440

Reaction notes

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