Cornforth reagent → HCID 15117891, compound

Participants

Reaction Steps

The above benzyl alcohol (37 g, 0.08 mol) in dichloromethane (150 ml) was added dropwise to a suspension of pyridinium dichromate (36.25 g, 0.14 mole, Tetrahedron Letters, 399 [1979]) in dichloromethane (250 ml), with stirring. Stirring was continued overnight, and then the reaction mixture was diluted with ether and filtered through a magnesium sulfatesilica gel pad. The filtrate was washed with 1N hydrochloric acid and then it was evaporated in vacuo to give 31.2 g (87% yield) of 2-(2-[2-(2-tetrahydropyranyloxy)ethoxy]ethoxy)-5-t-octylbenzaldehyde, as an oil.

Provenance & Evidence