HCID 14820755, compound → Propanoic acid, 2-(4-hydroxyphenoxy)-, ethyl ester

Participants

Reaction Steps

Ethyl 2-(4-acetoxyphenoxy)propionate (5.01 g, 19.9 mmol) is hydrolyzed by refluxing for 2 hours at 80° C. with ethanol (40 mL) and concentrated HCl (36%, 2 drops). The reaction product is concentrated under reduced pressure to obtain ethyl 2-(4-hydroxyphenoxy)propionate (3.8 g) (yield 93%), 1NMR (CHCl3) delta 1.25 (t, J=7.0 Hz, 3H), 1.62 (d, J=6.8 Hz, 3H), 4.21 (q, J=7.0 Hz, 2H), 4.65 (q, J=6.8 Hz, 1H), 6.74 (M, 4H).

Provenance & Evidence