HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,6-Trifluoro-5-hydroxyphthalic acid → 2,4,5-Trifluoro-3-hydroxybenzoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,6-Trifluoro-5-hydroxyphthalic acid | HCID 10198587 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2,4,5-Trifluoro-3-hydroxybenzoic Acid | HCID 2734270 | — |
Reaction Steps
Japanese Patent Application No. 86/290399 as abstracted in CA109 (19) 170038e discloses that 3,5,6-trifluoro-4-hydroxyphthalic acid may be decarboxylated by heating the compound for three hours, in water, under nitrogen atmosphere, at 140° C. (in a sealed tube) to yield 2,4,5-trifluoro-3-hydroxybenzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04935541 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-90dc6ea362394b629675d76b9f659ccc |
| Source note | uspto-grants-1990_06 |