Acetic Anhydride → HCID 14848179, compound

Participants

Reaction Conditions

Reaction Steps

A 200 cc titanium pressure vessel equipped with a stirrer was charged with 10 parts of 2-methyl-6-acetyloxynaphthalene, 80 parts of acetic acid, 20 parts of acetic anhydride, 0.249 parts (Co=590 wt. ppm) of cobalt acetate tetrahydrate, 0.245 parts (Mn=550 wt. ppm) of manganese acetate tetrahydrate, and 0.250 parts (Br=2040 wt. ppm) of ammonium bromide. The vessel was pressurized with air to 25 kg/cm2 -G, and the mixture was heated to 120° C. Air was introduced into the vessel at a rate of 10 Nl/hr. When the absorption of oxygen ceased, the reaction was terminated. The reaction time was 2.5 hours. The vessel was cooled, and the contents were withdrawn and analyzed. The conversion of 2-methyl-6-acetyloxynaphthalene was 100 mole %, and the yield of 6-acetyloxy-2-naphthoic acid was 68.5 mole % (selectivity 68.5 mole %). At this time, 23.5 mole % of 6-acetyloxy-2-naphthaldehyde was also formed.

Provenance & Evidence