6-(Acetyloxy)-2-naphthalenecarboxylic acid → HCID 14848179, compound

Participants

Reaction Steps

The 2-methyl-6-acetyloxynaphthalene obtained in the first half of Example 1 was not recrystallized from acetic anhydride prior to oxidation, but was directly oxidized with molecular oxygen in the presence of the same catalyst as in Example 1 in the same reactor as in Example 1. The reaction time was 2.4 hours. After the reaction, the product was analyzed. The conversion of 2-methyl-6-acetyloxynaphthalene was 55.5 mole %, and the yield of 6-acetyloxy-2-naphthoic acid was 40.0 mole % (selectivity 72 mole %). At this time, 8.88 mole % of 6-acetyloxy-2-naphthaldehyde was formed.

Provenance & Evidence