HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fmoc-succinimide → N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[(2,4,6-trimethoxyphenyl)methyl]-L-glutamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fmoc-succinimide | HCID 9883579 | — |
| Reactant | N'(2,4,6-trimethoxybenzyl)-L-glutamine | HCID 14836422 | — |
| Solvent | chloroform methanol HOAc | HCID 21866353 | — |
| Product | N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-[(2,4,6-trimethoxyphenyl)methyl]-L-glutamine | HCID 14442897 | — |
Reaction Steps
N'(2,4,6-trimethoxybenzyl)-L-glutamine (0.97 g, 3 mmol) was reacted with Fmoc-succinimide as described in Step 3 of Example 1 to give 1.23 g (78%), thin layer chromatography 1 spot Rf 0.35 chloroform/methanol/acetic acid (90:5:5).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04935536 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-23f3d8147de0416e874c9332bada9a55 |
| Source note | uspto-grants-1990_06 |