Nitric Acid → HCID 14421354, compound

HRID 2107879Notes

Reaction equation

HRID 2107879 reaction equation
C(OC(=O)C)(=O)C.[N+:8]([O-:11])(O)=[O:9].[CH3:12][S:13]([NH:16][C:17]1[N:21]([C:22]2[C:27]([Cl:28])=[CH:26][C:25]([C:29]([F:32])([F:31])[F:30])=[C:24]([F:33])[C:23]=2[Cl:34])[N:20]=[CH:19][CH:18]=1)(=[O:15])=[O:14].O>C(O)(=O)C>[CH3:12][S:13]([NH:16][C:17]1[N:21]([C:22]2[C:27]([Cl:28])=[CH:26][C:25]([C:29]([F:32])([F:30])[F:31])=[C:24]([F:33])[C:23]=2[Cl:34])[N:20]=[CH:19][C:18]=1[N+:8]([O-:11])=[O:9])(=[O:14])=[O:15]

Participants

6

Reactant 4

HCID 944Nitric AcidHCID 962WaterHCID 7918Acetic AnhydrideHCID 14421352HCID 14421352, compound

Product 1

HCID 14421354HCID 14421354, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

1.07 ml (0.011 mol) of acetic anhydride and 0.45 ml (0.0106 mol) of 98 percent strength nitric acid are added successively to a solution of 3.8 g (0.01 mol) of 5-methanesulphonamido-1-(2,6-dichloro-3-fluoro-4-trifluoromethylphenyl)-pyrazole in 20 ml of glacial acetic acid at approximately 15° C. The mixture is stirred at room temperature for approximately 16 hours, and the reaction solution is then poured into 100 ml of water. The precipiate thus formed is filtered off with suction, washed until neutral and dried in vacuo. 3.5 g (80% of theory) of 5-methanesulphonamido-4-nitro-1-(2,6-dichloro-3-fluoro-4-trifluoromethylphenyl)-pyrazole of melting point 107°-115° C. are obtained.

Workup

  1. customThe precipiate thus formed
  2. filtrationis filtered off with suction
  3. washwashed until neutral and
  4. customdried in vacuo

Sources & evidence

ORD record
ord-67e196173bc4405cb8abc3650a30be86
Source dataset
uspto-grants-1990_06
Patent number
US04936892

Reaction notes

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