Sodium Hydroxide → HCID 23673130, compound

HRID 2107889Notes

Reaction equation

HRID 2107889 reaction equation
[CH3:1][N:2]1[C:10]([CH3:11])=[CH:9][C:8](=[O:12])[C:4]([C:5]([OH:7])=[O:6])=[C:3]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[OH-].[Na+:20]>CO>[CH3:1][N:2]1[C:10]([CH3:11])=[CH:9][C:8](=[O:12])[C:4]([C:5]([O-:7])=[O:6])=[C:3]1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[Na+:20]

Participants

4

Reactant 2

HCID 14798Sodium Hydroxide2×HCID 14075272HCID 14075272, compound

Product 1

HCID 23673130HCID 23673130, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1.69 gms of 1,6-dimethyl-2-phenyl-4-oxonicotinic acid is suspended in approximately 50 mls of methanol. NaOH pellets (0.305 gms) are added with stirring. After both the acid and the sodium hydroxide dissolve the solution is evaporated to dryness in vacuo. Sodium 1,6-dimethyl-2-phenyl-4-oxonicotinate is then isolated as a glossy, somewhat hydroscopic solid. Yield=1.6 gms.

Workup

  1. customis evaporated to dryness in vacuo

Sources & evidence

ORD record
ord-93ace0bd222a48eca298e4b595b3e94e
Source dataset
uspto-grants-1990_06
Patent number
US04936904

Reaction notes

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