Sodium Hydroxide → HCID 23705003, compound

HRID 2107902Notes

Reaction equation

HRID 2107902 reaction equation
[CH3:1][N:2]1[C:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:9][C:8](=[O:17])[C:4]([C:5]([OH:7])=[O:6])=[C:3]1[CH3:18].[OH-].[Na+:20]>CO>[CH3:1][N:2]1[C:10]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[CH:9][C:8](=[O:17])[C:4]([C:5]([O-:7])=[O:6])=[C:3]1[CH3:18].[Na+:20]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 14075320HCID 14075320, compound

Product 1

HCID 23705003HCID 23705003, compoundYield 349.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

15 g (0.01617 mol) of 1,2-dimethyl-6-phenyl-4-oxonicotinic acid is suspended in 200 ml of methanol and to it there is added 2.71 g (0.0678 mol) of sodium hydroxide pellets. The solution formed is concentrated in vacuo to afford 15 g (92% yield) of product.

Workup

  1. customThe solution formed
  2. concentrationis concentrated in vacuo

Sources & evidence

ORD record
ord-9ba41b8544f84a0e95628984fc197378
Source dataset
uspto-grants-1990_06
Patent number
US04936904

Reaction notes

Loading…