Sodium Hydroxide → HCID 23705014, compound

HRID 2107928Notes

Reaction equation

HRID 2107928 reaction equation
[CH3:1][N:2]1[C:10]([C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=2)=[CH:9][C:8](=[O:18])[C:4]([C:5]([OH:7])=[O:6])=[C:3]1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[OH-].[Na+:26]>CO>[CH3:1][N:2]1[C:10]([C:11]2[CH:16]=[CH:15][C:14]([CH3:17])=[CH:13][CH:12]=2)=[CH:9][C:8](=[O:18])[C:4]([C:5]([O-:7])=[O:6])=[C:3]1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[Na+:26]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 14075377HCID 14075377, compound

Product 1

HCID 23705014HCID 23705014, compoundYield 87.7%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

0.64 gms of 1-methyl-2-phenyl-6-(4'-methylphenyl)-4-oxonicotinic acid, 0.09 gms of NaOH and 30 mls of methanol were mixed. Evaporation of the solvent provided 0.6 gms of sodium 1-methyl-2-phenyl-6-(4'-methylphenyl)-4-oxonicotinate as a glassy solid.

Workup

  1. customEvaporation of the solvent

Sources & evidence

ORD record
ord-c058c4d5c7194f08acab2e80c50fdcb5
Source dataset
uspto-grants-1990_06
Patent number
US04936904

Reaction notes

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