Sodium Hydroxide → HCID 23705001, compound

HRID 2107930Notes

Reaction equation

HRID 2107930 reaction equation
[Br:1][C:2]1[C:10](=[O:11])[C:6]([C:7]([OH:9])=[O:8])=[C:5]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[N:4]([CH3:18])[C:3]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[OH-].[Na+:26]>CO>[Br:1][C:2]1[C:10](=[O:11])[C:6]([C:7]([O-:9])=[O:8])=[C:5]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[N:4]([CH3:18])[C:3]=1[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[Na+:26]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 14075378HCID 14075378, compound

Product 1

HCID 23705001HCID 23705001, compoundYield 98.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2.5 gms of 5-bromo-1-methyl-2,6-diphenyl-4-oxonicotinic acid, 0.286 gms of NaOH and 50 mls of dry methanol were mixed. Evaporation of the solvent provided 2.6 gms of sodium 5-bromo-1-methyl-2,6-diphenyl-4-oxonicotinate as a tan glassy solid.

Workup

  1. customEvaporation of the solvent

Sources & evidence

ORD record
ord-8f063f1e90b442beb5b58a3ef2213700
Source dataset
uspto-grants-1990_06
Patent number
US04936904

Reaction notes

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