HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Aminohexanoic Acid → Dicyclohexylcarbodiimide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Aminohexanoic Acid | HCID 564 | — |
| Reactant | Trifluoroacetic anhydride | HCID 9845 | — |
| Reactant | HCID 19776314 | HCID 19776314 | — |
| Product | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Product | N-Hydroxysuccinimide | HCID 80170 | — |
Reaction Steps
ε-Aminocaproic acid is reacted with trifluoroacetic anhydride or trifluoroacetyl-N-hydroxysuccinimide and then dicyclohexylcarbodiimide and N-hydroxysuccinimide, giving ε-(trifluoracetamido) caproic acid N-hydroxysuccinimide ester (TFA-CA-NHS).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04937188 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-b564d068f1ce44c196e2803af1773f3c |
| Source note | uspto-grants-1990_06 |