HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Nitroquinolin-2(1H)-one → 6-Aminoquinolin-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Nitroquinolin-2(1H)-one | HCID 899932 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-Aminoquinolin-2-ol | HCID 12810797 | — |
Reaction Steps
In a Parr catalytic hydrogenation apparatus 6-nitrocarbostyril, 5.3 g (0.028 mole), in 150 mL of methanol and 0.5 g PtO2 were shaken in a hydrogen atmosphere. The resulting yellow solid was extracted with refluxing methanol to yield 6-aminocarbostyril, 3.5 g, as yellow crystals; m.p. 315°-317° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04937248 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-390a33c903264b73aa59ad8ac70748f8 |
| Source note | uspto-grants-1990_06 |