Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2108020Generated: October 27, 2026

1,6-Dibromohexane → 2-[2-[(6-Bromohexyl)oxy]ethyl]-6-methylpyridine

https://huagongshe.com/reaction/2108020

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,6-DibromohexaneHCID 12368—
Reactant6-Methylpyridine-2-ethanolHCID 70283—
SolventEthyl AcetateHCID 8857—
Product2-[2-[(6-Bromohexyl)oxy]ethyl]-6-methylpyridineHCID 2304504982.2%

Reaction Steps

From 6-methyl-2-pyridineethanol (5 g) and 1,6-dibromohexane (26 g), stirring the reaction mixture under nitrogen for 18 h, and using ethyl acetate for extraction. FCC eluting with cyclohexane→cyclohexane-ethyl acetate (92:8) gave the title compound as a yellow oil (9 g), t.l.c. (System A 80:20:1) Rf 0.6.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04937251
Source datasetuspto-grants-1990_06
ORD IDord-bfe72a7401c145ce9e3457386b7853d9
Source noteuspto-grants-1990_06