HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Hydroxyethyl)pyridine → 2-[2-(4-Bromobutoxy)ethyl]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Hydroxyethyl)pyridine | HCID 7675 | — |
| Reactant | 1,4-Dibromobutane | HCID 8056 | — |
| Product | 2-[2-(4-Bromobutoxy)ethyl]pyridine | HCID 23045072 | 61.1% |
Reaction Steps
From 2-pyridineethanol (5.0 g) and 1,4-dibromobutane (26.29 g), with a reaction time of 4 h. FCC eluting with ether-hexane (1:1) gave the title compound as a pale yellow oil (6.4 g), t.l.c. (ether-hexane 1:1) Rf 0.37.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04937251 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-700a49b178ca480f95329b8047d3a7fe |
| Source note | uspto-grants-1990_06 |