Benzylamine → HCID 23045075, compound

Participants

Reaction Steps

From 2-[2-[(5-bromopentyl)oxy]ethyl]pyridine (6.04 g) and benzylamine (33 ml). After 1 h at 130° the reaction mixture was cooled and partitioned between ethyl acetate (400 ml) and 8% aqueous sodium bicarbonate (250 ml). The final product was purified by FCC eluting with ethyl acetate-triethylamine (100:1) to give the title compound as a pale yellow oil (4.18 g), t.l.c. (ethyl acetate+few drops triethylamine) Rf 0.14.

Provenance & Evidence