HCID 23045067, compound → HCID 23045062, compound

Participants

Reaction Steps

A solution of 6-[2-(2-pyridinyl)ethoxy]hexanol (1.0 g) in dichloromethane (8 ml) was added dropwise over 15 min to a stirred suspension of pyridinium chlorochromate (1.83 g) and silica (Merck 7734, 2.9 g) in dichloromethane (30 ml). The mixture was stirred at room temperature under nitrogen for 4 h, diluted with ether (100 ml) and filtered through silica (Merck 9385, 200 ml), eluting with dichloromethane followed by methanol to give a brown oil. Purification by FCC eluting with ether gave the title compound as a yellow oil (0.49 g), t.l.c. (System A 40:10:1) Rf 0.42.

Provenance & Evidence