HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 6-hydroxy-2-(4-methoxyphenyl)chroman-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Acetylhydroquinone | HCID 10279 | — |
| Reactant | 4-Methoxybenzaldehyde | HCID 31244 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-hydroxy-2-(4-methoxyphenyl)chroman-4-one | HCID 11818079 | — |
| Product | HCID 70356590 | HCID 70356590 | — |
Reaction Steps
HCl is passed for 4 hours, with stirring, into a solution of 15.2 g of 2,5-dihydroxyacetophenone and 27.2 g of anisaldehyde in 1,500 ml of ethanol. 3-p-Methoxybenzylidene-6-hydroxy-4'-methoxyflavanone is precipitated, m.p. 199°-201°. 6-Hydroxy-4'-methoxyflavanone and 2,5-dihydroxy-p-methoxybenzylideneacetophenone are formed as intermediates.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04937257 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-e1e52db5d9484b699d1ca26b9f24b275 |
| Source note | uspto-grants-1990_06 |