HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl phenylmalonate → Diethyl 2-cyclohexylmalonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl phenylmalonate | HCID 66514 | — |
| Catalyst | Rhodium | HCID 23948 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Diethyl 2-cyclohexylmalonate | HCID 240541 | — |
Reaction Steps
A suspension of 5% rhodium on carbon (4.5 g) and diethyl phenylmalonate (30 g) in ethanol (100 ml) was hydrogenated at 60 psi for 18 hours. The suspension was filtered through celite and concentrated to a syrup (quant. yield). Distillation at 90°-94° C. (0.5 mmHg) afforded 28.2 g (92%) of the diethyl cyclohexylmalonate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04937355 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-14dd2840bad0418aa294601f9286977a |
| Source note | uspto-grants-1990_06 |