HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3-(Phenoxymethyl)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | HCID 178490745 | HCID 178490745 | — |
| Catalyst | HCID 178418751 | HCID 178418751 | — |
| Product | 3-(Phenoxymethyl)pyridine | HCID 12474431 | — |
Reaction Steps
This substance was prepared by a dichlorobis-(triphenylphosphine)nickel (II) catalyzed reaction between 3-methoxyphenylmagnesium bromide (from 50 g of 3-bromo-anisole and 5.9 g of Mg in THF) and 31.8 g of 3-bromopyridine. Yield 23.1 g (62%), bp. 102° /0.15 mmHg, mp. (HCl) 187.5-9° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04937346 |
| Source dataset | uspto-grants-1990_06 |
| ORD ID | ord-dff017cd530242a08ecf7417c43d050b |
| Source note | uspto-grants-1990_06 |