Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Phenol | HCID 996 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Dibenzofuran | HCID 568 | — |
Reaction Steps
The phenol 10 is dissolved in DMSO under nitrogen, a 60% sodium hydride/mineral oil suspension is added, and the mixture is warmed to 120° C. After 5 hours at this temperature, the cooled batch is added to dil. HCl solution. The aqueous phase is extracted with MTB ether. The organic phase is dried over sodium sulfate, evaporated and chromatographed on silica gel.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07514127B2 |
|---|
| Source dataset | uspto-grants-2009_04 |
|---|
| ORD ID | ord-043dc0a2b807409b8a6633c7a76e8f91 |
|---|
| Source note | uspto-grants-2009_04 |
|---|
