Benzylamine → HCID 68872594, compound

HRID 2108316Notes

Reaction equation

HRID 2108316 reaction equation
[F:1][C:2]([F:15])([CH2:9][C:10]([O:12]CC)=O)[CH2:3][C:4]([O:6]CC)=O.[CH2:16]([NH2:23])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[CH2:16]([N:23]1[C:4](=[O:6])[CH2:3][C:2]([F:1])([F:15])[CH2:9][C:10]1=[O:12])[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 12696177Diethyl 3,3-difluoropentanedioate

Product 1

HCID 68872594HCID 68872594, compound

Procedure

React an 8.1 mmol portion of the product of Example 14 with benzylamine using the general procedure set forth in Example 8, and purify by silica gel chromatography using ethyl acetate/hexane as eluant to yield the title compound.

Workup

  1. custompurify by silica gel chromatography

Sources & evidence

ORD record
ord-9b21c2ac84da40db9f19bae0bec19d6a
Source dataset
uspto-grants-2009_04
Patent number
US07514068B2

Reaction notes

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