Benzylamine → HCID 86611508, compound

HRID 2108318Notes

Reaction equation

HRID 2108318 reaction equation
[S:1]1[CH2:6][CH2:5][CH2:4][S:3][C:2]1([C:15]([F:22])([F:21])[C:16]([O:18]CC)=O)[C:7]([F:14])([F:13])[C:8]([O:10]CC)=O.[CH2:23]([NH2:30])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>>[CH2:23]([N:30]1[C:8](=[O:10])[C:7]([F:13])([F:14])[C:2]2([S:1][CH2:6][CH2:5][CH2:4][S:3]2)[C:15]([F:21])([F:22])[C:16]1=[O:18])[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 86611509HCID 86611509, compound

Product 1

HCID 86611508HCID 86611508, compound

Procedure

React 7.2 mmol of the product of Example 20 with benzylamine using the general procedure set forth in Example 8, and purify by silica gel chromatography using ethyl acetate/hexane as eluant to yield the title compound.

Workup

  1. custompurify by silica gel chromatography

Sources & evidence

ORD record
ord-d9811a4eaa9a4b9a9b778d4c25aa7679
Source dataset
uspto-grants-2009_04
Patent number
US07514068B2

Reaction notes

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