Aluminium lithium hydride → HCID 86611510, compound

HRID 2108319Notes

Reaction equation

HRID 2108319 reaction equation
[CH2:1]([N:8]1[C:18](=O)[C:17]([F:21])([F:20])[C:11]2([S:16][CH2:15][CH2:14][CH2:13][S:12]2)[C:10]([F:23])([F:22])[C:9]1=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:1]([N:8]1[CH2:9][C:10]([F:22])([F:23])[C:11]2([S:12][CH2:13][CH2:14][CH2:15][S:16]2)[C:17]([F:21])([F:20])[CH2:18]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 21226445Aluminium lithium hydrideHCID 86611508HCID 86611508, compound

Product 1

HCID 86611510HCID 86611510, compound

Procedure

React 4.9 mmol of the product of Example 21 with lithium aluminum hydride, using the general procedure set forth in Example 1. Purify by silica gel chromatography using methylene chloride/methanol/saturated NH4OH as eluant to yield the title compound.

Workup

  1. customPurify by silica gel chromatography

Sources & evidence

ORD record
ord-d930a1cc4e3e48a9bdc8d03dd8ac9dda
Source dataset
uspto-grants-2009_04
Patent number
US07514068B2

Reaction notes

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